| Pittsburgh to Des Plaines (Illinois) | 426.05 mi (685.65 km) |
| Pittsburgh to Desert Hot Springs (California) | 2,046.41 mi (3,293.38 km) |
| Pittsburgh to DeSoto (Texas) | 1,080.20 mi (1,738.41 km) |
| Pittsburgh to Destin (Florida) | 783.87 mi (1,261.52 km) |
| Pittsburgh to Destrehan (Louisiana) | 930.33 mi (1,497.22 km) |
| Pittsburgh to Detroit (Michigan) | 210.39 mi (338.59 km) |
| Pittsburgh to Diamond Bar (California) | 2,112.15 mi (3,399.18 km) |
| Pittsburgh to Diamond Springs (California) | 2,160.37 mi (3,476.78 km) |
| Pittsburgh to Dickinson (North Dakota) | 1,218.94 mi (1,961.69 km) |
| Pittsburgh to Dickinson (Texas) | 1,139.64 mi (1,834.08 km) |
| Pittsburgh to Dickson (Tennessee) | 501.89 mi (807.72 km) |
| Pittsburgh to Difficult Run (Virginia) | 175.62 mi (282.63 km) |
| Pittsburgh to Dinuba (California) | 2,131.03 mi (3,429.56 km) |
| Pittsburgh to Discovery Bay (California) | 2,215.72 mi (3,565.85 km) |
| Pittsburgh to Dix Hills (New York) | 348.98 mi (561.64 km) |
