| Piqua to Storm Lake (Iowa) | 592.68 mi (953.83 km) |
| Piqua to Storrs (Connecticut) | 635.40 mi (1,022.58 km) |
| Piqua to Stoughton (Wisconsin) | 320.85 mi (516.35 km) |
| Piqua to Stow (Ohio) | 163.42 mi (263.00 km) |
| Piqua to Streamwood (Illinois) | 242.17 mi (389.74 km) |
| Piqua to Streator (Illinois) | 249.63 mi (401.74 km) |
| Piqua to Streetsboro (Ohio) | 169.45 mi (272.70 km) |
| Piqua to Strongsville (Ohio) | 149.68 mi (240.89 km) |
| Piqua to Stuart (Florida) | 923.87 mi (1,486.82 km) |
| Piqua to Stuarts Draft (Virginia) | 315.73 mi (508.11 km) |
| Piqua to Sturgis (Michigan) | 129.32 mi (208.13 km) |
| Piqua to Suamico (Wisconsin) | 366.09 mi (589.17 km) |
| Piqua to Sudley (Virginia) | 371.93 mi (598.56 km) |
| Piqua to Suffern (New York) | 533.55 mi (858.67 km) |
| Piqua to Suffolk (Virginia) | 475.59 mi (765.39 km) |
