| Pierre to Enterprise (Nevada) | 973.77 mi (1,567.14 km) |
| Pierre to Enumclaw (Washington) | 1,058.53 mi (1,703.54 km) |
| Pierre to Ephrata (Pennsylvania) | 1,262.61 mi (2,031.97 km) |
| Pierre to Erie (Colorado) | 384.59 mi (618.95 km) |
| Pierre to Erie (Pennsylvania) | 1,028.18 mi (1,654.70 km) |
| Pierre to Erlanger (Kentucky) | 890.43 mi (1,433.01 km) |
| Pierre to Escanaba (Michigan) | 651.86 mi (1,049.07 km) |
| Pierre to Escondido (California) | 1,186.53 mi (1,909.53 km) |
| Pierre to Española (New Mexico) | 652.67 mi (1,050.37 km) |
| Pierre to Essex (Maryland) | 1,272.87 mi (2,048.49 km) |
| Pierre to Essex Junction (Vermont) | 1,336.08 mi (2,150.22 km) |
| Pierre to Estelle (Louisiana) | 1,148.89 mi (1,848.96 km) |
| Pierre to Estero (Florida) | 1,612.60 mi (2,595.23 km) |
| Pierre to Euclid (Ohio) | 967.35 mi (1,556.79 km) |
| Pierre to Eufaula (Alabama) | 1,188.30 mi (1,912.39 km) |
