| Picayune to Yonkers (New York) | 1,138.51 mi (1,832.25 km) |
| Picayune to Yorba Linda (California) | 1,653.72 mi (2,661.41 km) |
| Picayune to York (Pennsylvania) | 976.83 mi (1,572.05 km) |
| Picayune to Yorktown (Indiana) | 706.57 mi (1,137.12 km) |
| Picayune to Yorkville (Illinois) | 771.60 mi (1,241.76 km) |
| Picayune to Youngstown (Ohio) | 887.00 mi (1,427.49 km) |
| Picayune to Youngsville (Louisiana) | 141.87 mi (228.32 km) |
| Picayune to Ypsilanti (Michigan) | 875.81 mi (1,409.47 km) |
| Picayune to Yuba City (California) | 1,896.40 mi (3,051.96 km) |
| Picayune to Yucaipa (California) | 1,612.09 mi (2,594.41 km) |
| Picayune to Yucca Valley (California) | 1,576.69 mi (2,537.44 km) |
| Picayune to Yukon (Oklahoma) | 581.43 mi (935.72 km) |
| Picayune to Yulee (Florida) | 482.02 mi (775.74 km) |
| Picayune to Yuma (Arizona) | 1,468.10 mi (2,362.67 km) |
| Picayune to Zachary (Louisiana) | 89.14 mi (143.46 km) |
