| Picayune to University Place (Washington) | 2,087.03 mi (3,358.75 km) |
| Picayune to Upland (California) | 1,647.52 mi (2,651.43 km) |
| Picayune to Upper Arlington (Ohio) | 753.80 mi (1,213.12 km) |
| Picayune to Upper Grand Lagoon (Florida) | 235.75 mi (379.40 km) |
| Picayune to Upper Montclair (New Jersey) | 1,120.11 mi (1,802.64 km) |
| Picayune to Urbana (Illinois) | 666.98 mi (1,073.41 km) |
| Picayune to Urbana (Maryland) | 924.20 mi (1,487.36 km) |
| Picayune to Urbana (Ohio) | 740.56 mi (1,191.82 km) |
| Picayune to Urbandale (Iowa) | 800.69 mi (1,288.59 km) |
| Picayune to Utica (New York) | 1,176.45 mi (1,893.31 km) |
| Picayune to Uvalde (Texas) | 612.04 mi (984.99 km) |
| Picayune to Vacaville (California) | 1,906.97 mi (3,068.97 km) |
| Picayune to Vadnais Heights (Minnesota) | 1,020.36 mi (1,642.11 km) |
| Picayune to Vail (Arizona) | 1,243.64 mi (2,001.45 km) |
| Picayune to Valdosta (Georgia) | 380.46 mi (612.29 km) |
