| Picayune to Storm Lake (Iowa) | 890.59 mi (1,433.27 km) |
| Picayune to Storrs (Connecticut) | 1,241.24 mi (1,997.58 km) |
| Picayune to Stoughton (Wisconsin) | 856.53 mi (1,378.45 km) |
| Picayune to Stow (Ohio) | 867.19 mi (1,395.60 km) |
| Picayune to Streamwood (Illinois) | 798.11 mi (1,284.43 km) |
| Picayune to Streator (Illinois) | 733.37 mi (1,180.24 km) |
| Picayune to Streetsboro (Ohio) | 873.40 mi (1,405.60 km) |
| Picayune to Strongsville (Ohio) | 863.56 mi (1,389.77 km) |
| Picayune to Stuart (Florida) | 615.02 mi (989.77 km) |
| Picayune to Stuarts Draft (Virginia) | 796.75 mi (1,282.24 km) |
| Picayune to Sturgis (Michigan) | 813.53 mi (1,309.25 km) |
| Picayune to Suamico (Wisconsin) | 978.33 mi (1,574.47 km) |
| Picayune to Sudley (Virginia) | 895.34 mi (1,440.91 km) |
| Picayune to Suffern (New York) | 1,133.31 mi (1,823.89 km) |
| Picayune to Suffolk (Virginia) | 861.20 mi (1,385.97 km) |
