| Picayune to Seymour (Tennessee) | 502.77 mi (809.12 km) |
| Picayune to Shady Hills (Florida) | 453.04 mi (729.11 km) |
| Picayune to Shafter (California) | 1,738.00 mi (2,797.03 km) |
| Picayune to Shaker Heights (Ohio) | 880.90 mi (1,417.67 km) |
| Picayune to Shakopee (Minnesota) | 1,005.50 mi (1,618.20 km) |
| Picayune to Sharon (Pennsylvania) | 899.02 mi (1,446.84 km) |
| Picayune to Sharonville (Ohio) | 673.86 mi (1,084.47 km) |
| Picayune to Shasta Lake (California) | 1,952.65 mi (3,142.48 km) |
| Picayune to Shawnee (Kansas) | 654.31 mi (1,053.01 km) |
| Picayune to Shawnee (Oklahoma) | 537.99 mi (865.81 km) |
| Picayune to Sheboygan (Wisconsin) | 918.76 mi (1,478.59 km) |
| Picayune to Shelby (North Carolina) | 574.39 mi (924.39 km) |
| Picayune to Shelbyville (Indiana) | 659.70 mi (1,061.68 km) |
| Picayune to Shelbyville (Kentucky) | 587.49 mi (945.47 km) |
| Picayune to Shelbyville (Tennessee) | 390.54 mi (628.51 km) |
