| Picayune to Scottsboro (Alabama) | 353.76 mi (569.33 km) |
| Picayune to Scottsdale (Arizona) | 1,314.34 mi (2,115.22 km) |
| Picayune to Scranton (Pennsylvania) | 1,082.61 mi (1,742.29 km) |
| Picayune to Seabrook (Maryland) | 931.36 mi (1,498.87 km) |
| Picayune to Seabrook (Texas) | 326.74 mi (525.84 km) |
| Picayune to Seaford (New York) | 1,144.27 mi (1,841.53 km) |
| Picayune to Seagoville (Texas) | 430.12 mi (692.22 km) |
| Picayune to Seal Beach (California) | 1,670.94 mi (2,689.12 km) |
| Picayune to Searcy (Arkansas) | 346.69 mi (557.94 km) |
| Picayune to Seaside (California) | 1,888.41 mi (3,039.10 km) |
| Picayune to SeaTac (Washington) | 2,082.23 mi (3,351.03 km) |
| Picayune to Seattle (Washington) | 2,088.01 mi (3,360.32 km) |
| Picayune to Sebastian (Florida) | 585.96 mi (943.01 km) |
| Picayune to Sebring (Florida) | 539.48 mi (868.21 km) |
| Picayune to Secaucus (New Jersey) | 1,123.49 mi (1,808.09 km) |
