| Picayune to Oskaloosa (Iowa) | 761.63 mi (1,225.73 km) |
| Picayune to Oswego (Illinois) | 774.04 mi (1,245.70 km) |
| Picayune to Oswego (New York) | 1,148.17 mi (1,847.80 km) |
| Picayune to Otsego (Minnesota) | 1,040.16 mi (1,673.98 km) |
| Picayune to Ottawa (Illinois) | 749.30 mi (1,205.89 km) |
| Picayune to Ottawa (Kansas) | 641.46 mi (1,032.33 km) |
| Picayune to Ottumwa (Iowa) | 740.66 mi (1,191.97 km) |
| Picayune to Overland (Missouri) | 565.49 mi (910.07 km) |
| Picayune to Overland Park (Kansas) | 643.42 mi (1,035.48 km) |
| Picayune to Overlea (Maryland) | 961.20 mi (1,546.90 km) |
| Picayune to Oviedo (Florida) | 525.82 mi (846.23 km) |
| Picayune to Owasso (Oklahoma) | 532.95 mi (857.70 km) |
| Picayune to Owatonna (Minnesota) | 956.77 mi (1,539.78 km) |
| Picayune to Owensboro (Kentucky) | 520.10 mi (837.02 km) |
| Picayune to Owings Mills (Maryland) | 951.25 mi (1,530.89 km) |
