| Picayune to Orangeburg (South Carolina) | 554.70 mi (892.70 km) |
| Picayune to Orangevale (California) | 1,869.81 mi (3,009.17 km) |
| Picayune to Orchards (Washington) | 2,049.51 mi (3,298.36 km) |
| Picayune to Orcutt (California) | 1,805.56 mi (2,905.76 km) |
| Picayune to Oregon (Ohio) | 843.02 mi (1,356.72 km) |
| Picayune to Oregon (Wisconsin) | 856.42 mi (1,378.28 km) |
| Picayune to Oregon City (Oregon) | 2,044.57 mi (3,290.42 km) |
| Picayune to Orem (Utah) | 1,406.37 mi (2,263.34 km) |
| Picayune to Orinda (California) | 1,914.90 mi (3,081.74 km) |
| Picayune to Orland Park (Illinois) | 771.83 mi (1,242.13 km) |
| Picayune to Orlando (Florida) | 520.80 mi (838.14 km) |
| Picayune to Ormond Beach (Florida) | 520.19 mi (837.16 km) |
| Picayune to Oro Valley (Arizona) | 1,260.05 mi (2,027.86 km) |
| Picayune to Oroville (California) | 1,896.27 mi (3,051.76 km) |
| Picayune to Oshkosh (Wisconsin) | 934.08 mi (1,503.25 km) |
