| Picayune to Elyria (Ohio) | 859.63 mi (1,383.45 km) |
| Picayune to Emeryville (California) | 1,920.82 mi (3,091.27 km) |
| Picayune to Emmaus (Pennsylvania) | 1,052.46 mi (1,693.77 km) |
| Picayune to Emporia (Kansas) | 658.12 mi (1,059.15 km) |
| Picayune to Encinitas (California) | 1,624.85 mi (2,614.95 km) |
| Picayune to Endicott (New York) | 1,098.42 mi (1,767.74 km) |
| Picayune to Endwell (New York) | 1,100.96 mi (1,771.83 km) |
| Picayune to Englewood (Colorado) | 1,068.43 mi (1,719.47 km) |
| Picayune to Englewood (Florida) | 506.90 mi (815.78 km) |
| Picayune to Englewood (New Jersey) | 1,131.78 mi (1,821.43 km) |
| Picayune to Englewood (Ohio) | 712.03 mi (1,145.90 km) |
| Picayune to Enid (Oklahoma) | 622.41 mi (1,001.67 km) |
| Picayune to Ennis (Texas) | 428.66 mi (689.87 km) |
| Picayune to Ensley (Florida) | 142.78 mi (229.78 km) |
| Picayune to Enterprise (Alabama) | 233.31 mi (375.48 km) |
