| Picayune to Des Plaines (Illinois) | 800.78 mi (1,288.73 km) |
| Picayune to Desert Hot Springs (California) | 1,583.35 mi (2,548.16 km) |
| Picayune to DeSoto (Texas) | 446.65 mi (718.82 km) |
| Picayune to Destin (Florida) | 190.94 mi (307.29 km) |
| Picayune to Destrehan (Louisiana) | 57.19 mi (92.04 km) |
| Picayune to Detroit (Michigan) | 895.82 mi (1,441.68 km) |
| Picayune to Diamond Bar (California) | 1,656.34 mi (2,665.62 km) |
| Picayune to Diamond Springs (California) | 1,849.46 mi (2,976.42 km) |
| Picayune to Dickinson (North Dakota) | 1,329.34 mi (2,139.37 km) |
| Picayune to Dickinson (Texas) | 330.78 mi (532.33 km) |
| Picayune to Dickson (Tennessee) | 404.68 mi (651.28 km) |
| Picayune to Difficult Run (Virginia) | 906.44 mi (1,458.78 km) |
| Picayune to Dinuba (California) | 1,754.05 mi (2,822.88 km) |
| Picayune to Discovery Bay (California) | 1,883.62 mi (3,031.39 km) |
| Picayune to Dix Hills (New York) | 1,156.14 mi (1,860.63 km) |
