| Penrith to Southern Pines (North Carolina) | 3,772.41 mi (6,071.10 km) |
| Penrith to Southfield (Michigan) | 3,564.70 mi (5,736.82 km) |
| Penrith to Southgate (Michigan) | 3,575.55 mi (5,754.30 km) |
| Penrith to Southlake (Texas) | 4,560.88 mi (7,340.03 km) |
| Penrith to Spanaway (Washington) | 4,577.66 mi (7,367.04 km) |
| Penrith to Spanish Fork (Utah) | 4,665.01 mi (7,507.61 km) |
| Penrith to Spanish Lake (Missouri) | 4,002.00 mi (6,440.60 km) |
| Penrith to Spanish Springs (Nevada) | 4,932.81 mi (7,938.60 km) |
| Penrith to Sparks (Nevada) | 4,938.99 mi (7,948.54 km) |
| Penrith to Spartanburg (South Carolina) | 3,882.84 mi (6,248.82 km) |
| Penrith to Spearfish (South Dakota) | 4,179.60 mi (6,726.41 km) |
| Penrith to Speedway (Indiana) | 3,805.43 mi (6,124.25 km) |
| Penrith to Spencer (Iowa) | 3,959.10 mi (6,371.56 km) |
| Penrith to Spokane (Washington) | 4,412.84 mi (7,101.78 km) |
| Penrith to Spokane Valley (Washington) | 4,407.68 mi (7,093.48 km) |
