| Pembroke Pines to Southern Pines (North Carolina) | 636.69 mi (1,024.65 km) |
| Pembroke Pines to Southfield (Michigan) | 1,149.51 mi (1,849.96 km) |
| Pembroke Pines to Southgate (Michigan) | 1,130.52 mi (1,819.40 km) |
| Pembroke Pines to Southlake (Texas) | 1,117.26 mi (1,798.05 km) |
| Pembroke Pines to Spanaway (Washington) | 2,706.24 mi (4,355.27 km) |
| Pembroke Pines to Spanish Fork (Utah) | 2,042.44 mi (3,286.99 km) |
| Pembroke Pines to Spanish Lake (Missouri) | 1,052.33 mi (1,693.56 km) |
| Pembroke Pines to Spanish Springs (Nevada) | 2,446.34 mi (3,937.00 km) |
| Pembroke Pines to Sparks (Nevada) | 2,447.74 mi (3,939.26 km) |
| Pembroke Pines to Spartanburg (South Carolina) | 624.26 mi (1,004.65 km) |
| Pembroke Pines to Spearfish (South Dakota) | 1,827.07 mi (2,940.39 km) |
| Pembroke Pines to Speedway (Indiana) | 1,011.36 mi (1,627.62 km) |
| Pembroke Pines to Spencer (Iowa) | 1,448.31 mi (2,330.83 km) |
| Pembroke Pines to Spokane (Washington) | 2,501.21 mi (4,025.31 km) |
| Pembroke Pines to Spokane Valley (Washington) | 2,492.62 mi (4,011.49 km) |
