| Pembroke Dock to Storm Lake (Iowa) | 4,008.95 mi (6,451.78 km) |
| Pembroke Dock to Storrs (Connecticut) | 3,141.15 mi (5,055.19 km) |
| Pembroke Dock to Stoughton (Wisconsin) | 3,770.62 mi (6,068.22 km) |
| Pembroke Dock to Stow (Ohio) | 3,542.46 mi (5,701.04 km) |
| Pembroke Dock to Streamwood (Illinois) | 3,771.18 mi (6,069.13 km) |
| Pembroke Dock to Streator (Illinois) | 3,837.36 mi (6,175.64 km) |
| Pembroke Dock to Streetsboro (Ohio) | 3,536.13 mi (5,690.84 km) |
| Pembroke Dock to Strongsville (Ohio) | 3,552.41 mi (5,717.05 km) |
| Pembroke Dock to Stuart (Florida) | 4,152.19 mi (6,682.30 km) |
| Pembroke Dock to Stuarts Draft (Virginia) | 3,585.19 mi (5,769.81 km) |
| Pembroke Dock to Sturgis (Michigan) | 3,673.36 mi (5,911.71 km) |
| Pembroke Dock to Suamico (Wisconsin) | 3,650.37 mi (5,874.71 km) |
| Pembroke Dock to Sudley (Virginia) | 3,487.27 mi (5,612.22 km) |
| Pembroke Dock to Suffern (New York) | 3,248.16 mi (5,227.41 km) |
| Pembroke Dock to Suffolk (Virginia) | 3,545.62 mi (5,706.12 km) |
