| Pembroke Dock to Scottsboro (Alabama) | 4,030.56 mi (6,486.56 km) |
| Pembroke Dock to Scottsdale (Arizona) | 5,073.72 mi (8,165.37 km) |
| Pembroke Dock to Scranton (Pennsylvania) | 3,298.48 mi (5,308.39 km) |
| Pembroke Dock to Seabrook (Maryland) | 3,452.08 mi (5,555.58 km) |
| Pembroke Dock to Seabrook (Texas) | 4,647.13 mi (7,478.83 km) |
| Pembroke Dock to Seaford (New York) | 3,240.15 mi (5,214.51 km) |
| Pembroke Dock to Seagoville (Texas) | 4,551.14 mi (7,324.35 km) |
| Pembroke Dock to Seal Beach (California) | 5,285.04 mi (8,505.45 km) |
| Pembroke Dock to Searcy (Arkansas) | 4,231.23 mi (6,809.51 km) |
| Pembroke Dock to Seaside (California) | 5,245.79 mi (8,442.28 km) |
| Pembroke Dock to SeaTac (Washington) | 4,652.11 mi (7,486.84 km) |
| Pembroke Dock to Seattle (Washington) | 4,643.03 mi (7,472.23 km) |
| Pembroke Dock to Sebastian (Florida) | 4,133.07 mi (6,651.54 km) |
| Pembroke Dock to Sebring (Florida) | 4,189.47 mi (6,742.30 km) |
| Pembroke Dock to Secaucus (New Jersey) | 3,259.08 mi (5,244.99 km) |
