| Pembroke Dock to Enumclaw (Washington) | 4,656.91 mi (7,494.57 km) |
| Pembroke Dock to Ephrata (Pennsylvania) | 3,372.02 mi (5,426.74 km) |
| Pembroke Dock to Erie (Colorado) | 4,495.31 mi (7,234.50 km) |
| Pembroke Dock to Erie (Pennsylvania) | 3,446.97 mi (5,547.37 km) |
| Pembroke Dock to Erlanger (Kentucky) | 3,766.29 mi (6,061.25 km) |
| Pembroke Dock to Escanaba (Michigan) | 3,565.03 mi (5,737.35 km) |
| Pembroke Dock to Escondido (California) | 5,285.75 mi (8,506.59 km) |
| Pembroke Dock to Española (New Mexico) | 4,741.20 mi (7,630.22 km) |
| Pembroke Dock to Essex (Maryland) | 3,421.17 mi (5,505.84 km) |
| Pembroke Dock to Essex Junction (Vermont) | 3,068.41 mi (4,938.12 km) |
| Pembroke Dock to Estelle (Louisiana) | 4,432.82 mi (7,133.93 km) |
| Pembroke Dock to Estero (Florida) | 4,256.54 mi (6,850.24 km) |
| Pembroke Dock to Euclid (Ohio) | 3,527.74 mi (5,677.35 km) |
| Pembroke Dock to Eufaula (Alabama) | 4,125.88 mi (6,639.97 km) |
| Pembroke Dock to Eugene (Oregon) | 4,864.63 mi (7,828.86 km) |
