| Pearland to Southern Pines (North Carolina) | 1,005.59 mi (1,618.34 km) |
| Pearland to Southfield (Michigan) | 1,116.00 mi (1,796.03 km) |
| Pearland to Southgate (Michigan) | 1,103.71 mi (1,776.25 km) |
| Pearland to Southlake (Texas) | 258.31 mi (415.72 km) |
| Pearland to Spanaway (Washington) | 1,887.34 mi (3,037.39 km) |
| Pearland to Spanish Fork (Utah) | 1,174.82 mi (1,890.69 km) |
| Pearland to Spanish Lake (Missouri) | 701.24 mi (1,128.53 km) |
| Pearland to Spanish Springs (Nevada) | 1,543.53 mi (2,484.07 km) |
| Pearland to Sparks (Nevada) | 1,543.98 mi (2,484.80 km) |
| Pearland to Spartanburg (South Carolina) | 865.74 mi (1,393.27 km) |
| Pearland to Spearfish (South Dakota) | 1,131.60 mi (1,821.14 km) |
| Pearland to Speedway (Indiana) | 874.11 mi (1,406.74 km) |
| Pearland to Spencer (Iowa) | 938.93 mi (1,511.07 km) |
| Pearland to Spokane (Washington) | 1,717.22 mi (2,763.59 km) |
| Pearland to Spokane Valley (Washington) | 1,709.85 mi (2,751.73 km) |
