| Pascagoula to Southern Pines (North Carolina) | 626.87 mi (1,008.84 km) |
| Pascagoula to Southfield (Michigan) | 886.41 mi (1,426.54 km) |
| Pascagoula to Southgate (Michigan) | 869.93 mi (1,400.02 km) |
| Pascagoula to Southlake (Texas) | 536.22 mi (862.96 km) |
| Pascagoula to Spanaway (Washington) | 2,135.65 mi (3,437.00 km) |
| Pascagoula to Spanish Fork (Utah) | 1,460.52 mi (2,350.48 km) |
| Pascagoula to Spanish Lake (Missouri) | 589.44 mi (948.62 km) |
| Pascagoula to Spanish Springs (Nevada) | 1,863.00 mi (2,998.22 km) |
| Pascagoula to Sparks (Nevada) | 1,864.42 mi (3,000.49 km) |
| Pascagoula to Spartanburg (South Carolina) | 498.35 mi (802.02 km) |
| Pascagoula to Spearfish (South Dakota) | 1,281.60 mi (2,062.53 km) |
| Pascagoula to Speedway (Indiana) | 664.16 mi (1,068.86 km) |
| Pascagoula to Spencer (Iowa) | 954.88 mi (1,536.73 km) |
| Pascagoula to Spokane (Washington) | 1,938.52 mi (3,119.75 km) |
| Pascagoula to Spokane Valley (Washington) | 1,930.21 mi (3,106.37 km) |
