| Parkway to Superior (Colorado) | 876.56 mi (1,410.69 km) |
| Parkway to Superior (Wisconsin) | 1,586.18 mi (2,552.71 km) |
| Parkway to Surprise (Arizona) | 602.31 mi (969.32 km) |
| Parkway to Susanville (California) | 140.09 mi (225.45 km) |
| Parkway to Sussex (Wisconsin) | 1,754.90 mi (2,824.24 km) |
| Parkway to Suwanee (Georgia) | 2,090.40 mi (3,364.17 km) |
| Parkway to Swansea (Illinois) | 1,692.45 mi (2,723.73 km) |
| Parkway to Sweetwater (Florida) | 2,534.39 mi (4,078.71 km) |
| Parkway to Sweetwater (Texas) | 1,251.62 mi (2,014.29 km) |
| Parkway to Sycamore (Illinois) | 1,734.21 mi (2,790.95 km) |
| Parkway to Sylacauga (Alabama) | 1,992.65 mi (3,206.85 km) |
| Parkway to Sylvania (Ohio) | 1,990.86 mi (3,203.99 km) |
| Parkway to Syosset (New York) | 2,523.65 mi (4,061.43 km) |
| Parkway to Syracuse (New York) | 2,362.53 mi (3,802.12 km) |
| Parkway to Syracuse (Utah) | 528.85 mi (851.09 km) |
