| Parkway to Stephenville (Texas) | 1,374.78 mi (2,212.49 km) |
| Parkway to Sterling (Colorado) | 981.80 mi (1,580.06 km) |
| Parkway to Sterling (Illinois) | 1,682.85 mi (2,708.29 km) |
| Parkway to Sterling (Virginia) | 2,349.95 mi (3,781.88 km) |
| Parkway to Sterling Heights (Michigan) | 2,019.48 mi (3,250.04 km) |
| Parkway to Steubenville (Ohio) | 2,161.81 mi (3,479.09 km) |
| Parkway to Stevens Point (Wisconsin) | 1,690.50 mi (2,720.60 km) |
| Parkway to Stevenson Ranch (California) | 325.49 mi (523.82 km) |
| Parkway to Stillwater (Minnesota) | 1,533.51 mi (2,467.94 km) |
| Parkway to Stillwater (Oklahoma) | 1,345.54 mi (2,165.44 km) |
| Parkway to Stockbridge (Georgia) | 2,094.03 mi (3,370.02 km) |
| Parkway to Stockton (California) | 36.92 mi (59.42 km) |
| Parkway to Stone Ridge (Virginia) | 2,343.29 mi (3,771.17 km) |
| Parkway to Stonecrest (Georgia) | 2,095.24 mi (3,371.96 km) |
| Parkway to Stony Brook (New York) | 2,541.39 mi (4,089.98 km) |
