| Parkway to St. Simons (Georgia) | 2,308.81 mi (3,715.67 km) |
| Parkway to Stafford (Texas) | 1,596.54 mi (2,569.38 km) |
| Parkway to Stallings (North Carolina) | 2,250.42 mi (3,621.69 km) |
| Parkway to Stamford (Connecticut) | 2,516.54 mi (4,049.98 km) |
| Parkway to Stanford (California) | 83.82 mi (134.90 km) |
| Parkway to Stanton (California) | 377.60 mi (607.69 km) |
| Parkway to Star (Idaho) | 442.48 mi (712.10 km) |
| Parkway to Starkville (Mississippi) | 1,846.87 mi (2,972.26 km) |
| Parkway to State College (Pennsylvania) | 2,300.85 mi (3,702.87 km) |
| Parkway to Staten Island (New York) | 2,494.00 mi (4,013.71 km) |
| Parkway to Statesboro (Georgia) | 2,253.82 mi (3,627.17 km) |
| Parkway to Statesville (North Carolina) | 2,224.88 mi (3,580.59 km) |
| Parkway to Staunton (Virginia) | 2,276.94 mi (3,664.38 km) |
| Parkway to Steamboat Springs (Colorado) | 790.92 mi (1,272.86 km) |
| Parkway to Steiner Ranch (Texas) | 1,449.96 mi (2,333.48 km) |
