| Parkway to Silver Firs (Washington) | 647.95 mi (1,042.77 km) |
| Parkway to Silver Spring (Maryland) | 2,370.06 mi (3,814.24 km) |
| Parkway to Silver Springs Shores (Florida) | 2,335.69 mi (3,758.93 km) |
| Parkway to Silverdale (Washington) | 636.39 mi (1,024.18 km) |
| Parkway to Silverton (Oregon) | 454.53 mi (731.50 km) |
| Parkway to Simi Valley (California) | 328.81 mi (529.17 km) |
| Parkway to Simpsonville (South Carolina) | 2,172.84 mi (3,496.85 km) |
| Parkway to Sioux City (Iowa) | 1,340.20 mi (2,156.85 km) |
| Parkway to Sioux Falls (South Dakota) | 1,329.41 mi (2,139.48 km) |
| Parkway to Skokie (Illinois) | 1,782.34 mi (2,868.40 km) |
| Parkway to Sleepy Hollow (New York) | 2,500.71 mi (4,024.51 km) |
| Parkway to Slidell (Louisiana) | 1,881.89 mi (3,028.62 km) |
| Parkway to Smithfield (North Carolina) | 2,365.48 mi (3,806.87 km) |
| Parkway to Smithfield (Utah) | 557.60 mi (897.37 km) |
| Parkway to Smithville (Missouri) | 1,440.28 mi (2,317.91 km) |
