| Parkway to Santa Rosa (California) | 67.97 mi (109.39 km) |
| Parkway to Santaquin (Utah) | 526.48 mi (847.29 km) |
| Parkway to Santee (California) | 463.44 mi (745.84 km) |
| Parkway to Sapulpa (Oklahoma) | 1,400.32 mi (2,253.59 km) |
| Parkway to Saraland (Alabama) | 1,955.63 mi (3,147.28 km) |
| Parkway to Sarasota (Florida) | 2,364.58 mi (3,805.42 km) |
| Parkway to Sarasota Springs (Florida) | 2,369.26 mi (3,812.96 km) |
| Parkway to Saratoga (California) | 90.63 mi (145.85 km) |
| Parkway to Saratoga Springs (New York) | 2,480.33 mi (3,991.70 km) |
| Parkway to Saratoga Springs (Utah) | 524.44 mi (844.01 km) |
| Parkway to Sartell (Minnesota) | 1,472.45 mi (2,369.69 km) |
| Parkway to Satellite Beach (Florida) | 2,441.41 mi (3,929.07 km) |
| Parkway to Sauk Rapids (Minnesota) | 1,475.39 mi (2,374.42 km) |
| Parkway to Sault Ste. Marie (Michigan) | 1,948.09 mi (3,135.15 km) |
| Parkway to Savage (Minnesota) | 1,505.14 mi (2,422.29 km) |
