| Parkway to Olympia (Washington) | 594.72 mi (957.11 km) |
| Parkway to Olympia Heights (Florida) | 2,538.30 mi (4,085.00 km) |
| Parkway to Omaha (Nebraska) | 1,355.21 mi (2,181.00 km) |
| Parkway to On Top of the World Designated Place (Florida) | 2,321.25 mi (3,735.69 km) |
| Parkway to Onalaska (Wisconsin) | 1,606.26 mi (2,585.03 km) |
| Parkway to Oneida (New York) | 2,386.23 mi (3,840.26 km) |
| Parkway to Oneonta (New York) | 2,422.73 mi (3,899.01 km) |
| Parkway to Ontario (California) | 375.21 mi (603.85 km) |
| Parkway to Ontario (Oregon) | 446.88 mi (719.18 km) |
| Parkway to Opa-locka (Florida) | 2,536.62 mi (4,082.29 km) |
| Parkway to Opelika (Alabama) | 2,053.34 mi (3,304.53 km) |
| Parkway to Opelousas (Louisiana) | 1,751.78 mi (2,819.22 km) |
| Parkway to Orange (California) | 382.37 mi (615.36 km) |
| Parkway to Orange (Texas) | 1,675.15 mi (2,695.90 km) |
| Parkway to Orange City (Florida) | 2,380.43 mi (3,830.93 km) |
