| Parkersburg to Superior (Colorado) | 1,254.52 mi (2,018.95 km) |
| Parkersburg to Superior (Wisconsin) | 738.75 mi (1,188.90 km) |
| Parkersburg to Surprise (Arizona) | 1,751.06 mi (2,818.06 km) |
| Parkersburg to Susanville (California) | 2,057.32 mi (3,310.93 km) |
| Parkersburg to Sussex (Wisconsin) | 438.18 mi (705.17 km) |
| Parkersburg to Suwanee (Georgia) | 386.31 mi (621.70 km) |
| Parkersburg to Swansea (Illinois) | 456.48 mi (734.63 km) |
| Parkersburg to Sweetwater (Florida) | 934.09 mi (1,503.27 km) |
| Parkersburg to Sweetwater (Texas) | 1,153.03 mi (1,855.63 km) |
| Parkersburg to Sycamore (Illinois) | 419.15 mi (674.56 km) |
| Parkersburg to Sylacauga (Alabama) | 495.70 mi (797.75 km) |
| Parkersburg to Sylvania (Ohio) | 203.87 mi (328.10 km) |
| Parkersburg to Syosset (New York) | 438.46 mi (705.63 km) |
| Parkersburg to Syracuse (New York) | 383.29 mi (616.84 km) |
| Parkersburg to Syracuse (Utah) | 1,608.34 mi (2,588.37 km) |
