| Panama City to Enterprise (Nevada) | 1,753.84 mi (2,822.54 km) |
| Panama City to Enumclaw (Washington) | 2,257.31 mi (3,632.78 km) |
| Panama City to Ephrata (Pennsylvania) | 869.78 mi (1,399.77 km) |
| Panama City to Erie (Colorado) | 1,287.65 mi (2,072.28 km) |
| Panama City to Erie (Pennsylvania) | 878.71 mi (1,414.15 km) |
| Panama City to Erlanger (Kentucky) | 611.52 mi (984.15 km) |
| Panama City to Escanaba (Michigan) | 1,077.28 mi (1,733.72 km) |
| Panama City to Escondido (California) | 1,854.88 mi (2,985.15 km) |
| Panama City to Española (New Mexico) | 1,247.85 mi (2,008.23 km) |
| Panama City to Essex (Maryland) | 814.93 mi (1,311.51 km) |
| Panama City to Essex Junction (Vermont) | 1,199.14 mi (1,929.82 km) |
| Panama City to Estelle (Louisiana) | 270.41 mi (435.18 km) |
| Panama City to Estero (Florida) | 348.50 mi (560.86 km) |
| Panama City to Euclid (Ohio) | 819.24 mi (1,318.44 km) |
| Panama City to Eufaula (Alabama) | 121.16 mi (194.99 km) |
