| Panama City to Sesena | 4,514.93 mi (7,266.08 km) |
| Panama City to Sestao | 4,475.84 mi (7,203.17 km) |
| Panama City to Sevilla | 4,465.39 mi (7,186.35 km) |
| Panama City to Sevilla La Nueva | 4,492.86 mi (7,230.56 km) |
| Panama City to Silla | 4,696.45 mi (7,558.21 km) |
| Panama City to Silleda | 4,236.26 mi (6,817.60 km) |
| Panama City to Sitges | 4,756.33 mi (7,654.57 km) |
| Panama City to Socuellamos | 4,579.30 mi (7,369.67 km) |
| Panama City to Soller | 4,838.88 mi (7,787.42 km) |
| Panama City to Solsona | 4,722.94 mi (7,600.83 km) |
| Panama City to Son Servera | 4,875.08 mi (7,845.69 km) |
| Panama City to Sonseca | 4,511.77 mi (7,260.99 km) |
| Panama City to Sopelana | 4,475.54 mi (7,202.69 km) |
| Panama City to Soria | 4,536.78 mi (7,301.24 km) |
| Panama City to Suances | 4,423.39 mi (7,118.76 km) |
