| Panama City to Entroncamento | 4,288.97 mi (6,902.43 km) |
| Panama City to Ericeira | 4,250.85 mi (6,841.09 km) |
| Panama City to Ermezinde | 4,249.36 mi (6,838.68 km) |
| Panama City to Esmoriz | 4,250.70 mi (6,840.83 km) |
| Panama City to Espinho | 4,248.96 mi (6,838.04 km) |
| Panama City to Esposende | 4,231.57 mi (6,810.06 km) |
| Panama City to Estarreja | 4,257.79 mi (6,852.26 km) |
| Panama City to Estoril | 4,257.18 mi (6,851.27 km) |
| Panama City to Estremoz | 4,347.15 mi (6,996.06 km) |
| Panama City to Evora | 4,337.07 mi (6,979.83 km) |
| Panama City to Fafe | 4,263.81 mi (6,861.94 km) |
| Panama City to Falagueira | 4,264.90 mi (6,863.69 km) |
| Panama City to Famalicao | 4,247.09 mi (6,835.03 km) |
| Panama City to Fanzeres | 4,251.18 mi (6,841.62 km) |
| Panama City to Faro | 4,369.46 mi (7,031.97 km) |
