| Palmdale to Enterprise (Nevada) | 189.43 mi (304.86 km) |
| Palmdale to Enumclaw (Washington) | 894.09 mi (1,438.89 km) |
| Palmdale to Ephrata (Pennsylvania) | 2,311.93 mi (3,720.69 km) |
| Palmdale to Erie (Colorado) | 809.42 mi (1,302.63 km) |
| Palmdale to Erie (Pennsylvania) | 2,106.52 mi (3,390.12 km) |
| Palmdale to Erlanger (Kentucky) | 1,868.55 mi (3,007.15 km) |
| Palmdale to Escanaba (Michigan) | 1,794.72 mi (2,888.32 km) |
| Palmdale to Escondido (California) | 116.98 mi (188.27 km) |
| Palmdale to Española (New Mexico) | 685.27 mi (1,102.84 km) |
| Palmdale to Essex (Maryland) | 2,302.84 mi (3,706.07 km) |
| Palmdale to Essex Junction (Vermont) | 2,459.16 mi (3,957.63 km) |
| Palmdale to Estelle (Louisiana) | 1,663.86 mi (2,677.72 km) |
| Palmdale to Estero (Florida) | 2,220.93 mi (3,574.23 km) |
| Palmdale to Euclid (Ohio) | 2,031.14 mi (3,268.81 km) |
| Palmdale to Eufaula (Alabama) | 1,904.74 mi (3,065.38 km) |
