| Palm Coast to Superior (Colorado) | 1,529.13 mi (2,460.90 km) |
| Palm Coast to Superior (Wisconsin) | 1,320.66 mi (2,125.40 km) |
| Palm Coast to Surprise (Arizona) | 1,851.25 mi (2,979.30 km) |
| Palm Coast to Susanville (California) | 2,330.06 mi (3,749.87 km) |
| Palm Coast to Sussex (Wisconsin) | 1,015.52 mi (1,634.32 km) |
| Palm Coast to Suwanee (Georgia) | 353.03 mi (568.15 km) |
| Palm Coast to Swansea (Illinois) | 797.93 mi (1,284.15 km) |
| Palm Coast to Sweetwater (Florida) | 265.21 mi (426.81 km) |
| Palm Coast to Sweetwater (Texas) | 1,151.17 mi (1,852.63 km) |
| Palm Coast to Sycamore (Illinois) | 955.37 mi (1,537.53 km) |
| Palm Coast to Sylacauga (Alabama) | 388.18 mi (624.72 km) |
| Palm Coast to Sylvania (Ohio) | 852.14 mi (1,371.39 km) |
| Palm Coast to Syosset (New York) | 892.58 mi (1,436.46 km) |
| Palm Coast to Syracuse (New York) | 974.68 mi (1,568.60 km) |
| Palm Coast to Syracuse (Utah) | 1,899.03 mi (3,056.19 km) |
