| Ottawa to Southern Pines (North Carolina) | 664.50 mi (1,069.42 km) |
| Ottawa to Southfield (Michigan) | 296.38 mi (476.98 km) |
| Ottawa to Southgate (Michigan) | 295.41 mi (475.41 km) |
| Ottawa to Southlake (Texas) | 738.84 mi (1,189.05 km) |
| Ottawa to Spanaway (Washington) | 1,696.03 mi (2,729.50 km) |
| Ottawa to Spanish Fork (Utah) | 1,194.12 mi (1,921.74 km) |
| Ottawa to Spanish Lake (Missouri) | 191.82 mi (308.70 km) |
| Ottawa to Spanish Springs (Nevada) | 1,616.02 mi (2,600.74 km) |
| Ottawa to Sparks (Nevada) | 1,619.85 mi (2,606.90 km) |
| Ottawa to Spartanburg (South Carolina) | 579.95 mi (933.34 km) |
| Ottawa to Spearfish (South Dakota) | 787.42 mi (1,267.24 km) |
| Ottawa to Speedway (Indiana) | 173.04 mi (278.49 km) |
| Ottawa to Spencer (Iowa) | 346.35 mi (557.39 km) |
| Ottawa to Spokane (Washington) | 1,465.80 mi (2,358.98 km) |
| Ottawa to Spokane Valley (Washington) | 1,456.60 mi (2,344.17 km) |
