| Orangeburg to Worthington (Ohio) | 471.43 mi (758.70 km) |
| Orangeburg to Wright (Florida) | 398.56 mi (641.41 km) |
| Orangeburg to Wyandanch (New York) | 649.30 mi (1,044.94 km) |
| Orangeburg to Wyandotte (Michigan) | 615.12 mi (989.95 km) |
| Orangeburg to Wylie (Texas) | 903.77 mi (1,454.48 km) |
| Orangeburg to Wyndham (Virginia) | 342.92 mi (551.88 km) |
| Orangeburg to Wyoming (Michigan) | 700.18 mi (1,126.83 km) |
| Orangeburg to Wyomissing (Pennsylvania) | 544.25 mi (875.88 km) |
| Orangeburg to Xenia (Ohio) | 460.36 mi (740.88 km) |
| Orangeburg to Yakima (Washington) | 2,256.23 mi (3,631.05 km) |
| Orangeburg to Yankton (South Dakota) | 1,104.36 mi (1,777.29 km) |
| Orangeburg to Yauco (Puerto Rico) | 1,375.39 mi (2,213.48 km) |
| Orangeburg to Yazoo City (Mississippi) | 553.24 mi (890.36 km) |
| Orangeburg to Yeadon (Pennsylvania) | 542.56 mi (873.17 km) |
| Orangeburg to Yelm (Washington) | 2,356.99 mi (3,793.21 km) |
