| Orangeburg to St. George (Utah) | 1,852.09 mi (2,980.65 km) |
| Orangeburg to St. Helens (Oregon) | 2,356.75 mi (3,792.82 km) |
| Orangeburg to St. James (New York) | 663.18 mi (1,067.29 km) |
| Orangeburg to St. John (Indiana) | 657.42 mi (1,058.01 km) |
| Orangeburg to St. Joseph (Missouri) | 885.18 mi (1,424.56 km) |
| Orangeburg to St. Louis (Missouri) | 632.40 mi (1,017.75 km) |
| Orangeburg to St. Louis Park (Minnesota) | 1,033.86 mi (1,663.83 km) |
| Orangeburg to St. Marys (Georgia) | 193.49 mi (311.40 km) |
| Orangeburg to St. Marys (Pennsylvania) | 564.91 mi (909.13 km) |
| Orangeburg to St. Matthews (Kentucky) | 423.40 mi (681.40 km) |
| Orangeburg to St. Michael (Minnesota) | 1,057.49 mi (1,701.87 km) |
| Orangeburg to St. Paul (Minnesota) | 1,024.94 mi (1,649.48 km) |
| Orangeburg to St. Peter (Minnesota) | 1,025.34 mi (1,650.12 km) |
| Orangeburg to St. Peters (Missouri) | 654.30 mi (1,052.99 km) |
| Orangeburg to St. Petersburg (Florida) | 408.04 mi (656.67 km) |
