| Orangeburg to Somersworth (New Hampshire) | 863.03 mi (1,388.90 km) |
| Orangeburg to Somerton (Arizona) | 1,951.69 mi (3,140.94 km) |
| Orangeburg to Somerville (Massachusetts) | 811.95 mi (1,306.70 km) |
| Orangeburg to Somerville (New Jersey) | 598.14 mi (962.61 km) |
| Orangeburg to Sonoma (California) | 2,331.89 mi (3,752.81 km) |
| Orangeburg to Soquel (California) | 2,312.84 mi (3,722.15 km) |
| Orangeburg to South Bend (Indiana) | 637.81 mi (1,026.45 km) |
| Orangeburg to South Bradenton (Florida) | 429.05 mi (690.49 km) |
| Orangeburg to South Burlington (Vermont) | 861.11 mi (1,385.82 km) |
| Orangeburg to South Charleston (West Virginia) | 338.43 mi (544.65 km) |
| Orangeburg to South Daytona (Florida) | 299.09 mi (481.33 km) |
| Orangeburg to South El Monte (California) | 2,123.93 mi (3,418.13 km) |
| Orangeburg to South Elgin (Illinois) | 713.67 mi (1,148.54 km) |
| Orangeburg to South Euclid (Ohio) | 556.07 mi (894.90 km) |
| Orangeburg to South Farmingdale (New York) | 644.72 mi (1,037.57 km) |
