| Orangeburg to Shoreview (Minnesota) | 1,032.85 mi (1,662.21 km) |
| Orangeburg to Shorewood (Illinois) | 684.65 mi (1,101.84 km) |
| Orangeburg to Shorewood (Wisconsin) | 763.98 mi (1,229.51 km) |
| Orangeburg to Short Hills (New Jersey) | 616.40 mi (991.99 km) |
| Orangeburg to Short Pump (Virginia) | 340.52 mi (548.02 km) |
| Orangeburg to Show Low (Arizona) | 1,668.43 mi (2,685.08 km) |
| Orangeburg to Shreveport (Louisiana) | 752.20 mi (1,210.54 km) |
| Orangeburg to Sicklerville (New Jersey) | 540.75 mi (870.25 km) |
| Orangeburg to Sidney (Ohio) | 503.63 mi (810.51 km) |
| Orangeburg to Sierra Madre (California) | 2,122.68 mi (3,416.12 km) |
| Orangeburg to Sierra Vista (Arizona) | 1,714.95 mi (2,759.94 km) |
| Orangeburg to Sierra Vista Southeast (Arizona) | 1,710.89 mi (2,753.41 km) |
| Orangeburg to Signal Hill (California) | 2,133.59 mi (3,433.68 km) |
| Orangeburg to Sikeston (Missouri) | 545.06 mi (877.20 km) |
| Orangeburg to Siloam Springs (Arkansas) | 796.15 mi (1,281.28 km) |
