| Orangeburg to Shelton (Connecticut) | 685.95 mi (1,103.93 km) |
| Orangeburg to Shelton (Washington) | 2,382.30 mi (3,833.95 km) |
| Orangeburg to Shenandoah (Louisiana) | 631.05 mi (1,015.58 km) |
| Orangeburg to Shepherdsville (Kentucky) | 411.77 mi (662.68 km) |
| Orangeburg to Sheridan (Wyoming) | 1,591.52 mi (2,561.31 km) |
| Orangeburg to Sherman (Texas) | 906.28 mi (1,458.51 km) |
| Orangeburg to Sherrelwood (Colorado) | 1,402.48 mi (2,257.08 km) |
| Orangeburg to Sherwood (Arkansas) | 654.40 mi (1,053.15 km) |
| Orangeburg to Sherwood (Oregon) | 2,354.51 mi (3,789.22 km) |
| Orangeburg to Shiloh (Illinois) | 614.28 mi (988.60 km) |
| Orangeburg to Shiloh (Ohio) | 474.92 mi (764.32 km) |
| Orangeburg to Shiloh (Pennsylvania) | 501.25 mi (806.68 km) |
| Orangeburg to Shirley (New York) | 668.87 mi (1,076.45 km) |
| Orangeburg to Shively (Kentucky) | 426.93 mi (687.08 km) |
| Orangeburg to Shoreline (Washington) | 2,352.39 mi (3,785.81 km) |
