| Orangeburg to San Luis Obispo (California) | 2,257.74 mi (3,633.48 km) |
| Orangeburg to San Marcos (California) | 2,085.63 mi (3,356.50 km) |
| Orangeburg to San Marcos (Texas) | 1,032.90 mi (1,662.30 km) |
| Orangeburg to San Marino (California) | 2,126.75 mi (3,422.67 km) |
| Orangeburg to San Mateo (California) | 2,328.61 mi (3,747.53 km) |
| Orangeburg to San Pablo (California) | 2,327.52 mi (3,745.79 km) |
| Orangeburg to San Rafael (California) | 2,337.08 mi (3,761.17 km) |
| Orangeburg to San Ramon (California) | 2,306.74 mi (3,712.34 km) |
| Orangeburg to San Tan Valley (Arizona) | 1,765.52 mi (2,841.33 km) |
| Orangeburg to Sand Springs (Oklahoma) | 883.75 mi (1,422.26 km) |
| Orangeburg to Sandusky (Ohio) | 558.67 mi (899.09 km) |
| Orangeburg to Sandy (Oregon) | 2,327.11 mi (3,745.13 km) |
| Orangeburg to Sandy (Utah) | 1,767.32 mi (2,844.23 km) |
| Orangeburg to Sandy Springs (Georgia) | 203.65 mi (327.74 km) |
| Orangeburg to Sanford (Florida) | 325.89 mi (524.47 km) |
