| Orangeburg to San Diego (California) | 2,086.71 mi (3,358.24 km) |
| Orangeburg to San Diego Country Estates (California) | 2,065.28 mi (3,323.74 km) |
| Orangeburg to San Dimas (California) | 2,109.74 mi (3,395.30 km) |
| Orangeburg to San Fernando (California) | 2,143.08 mi (3,448.95 km) |
| Orangeburg to San Francisco (California) | 2,334.43 mi (3,756.90 km) |
| Orangeburg to San Gabriel (California) | 2,126.26 mi (3,421.88 km) |
| Orangeburg to San Germán (Puerto Rico) | 1,365.54 mi (2,197.62 km) |
| Orangeburg to San Jacinto (California) | 2,067.11 mi (3,326.69 km) |
| Orangeburg to San Jose (California) | 2,305.06 mi (3,709.64 km) |
| Orangeburg to San Juan (Puerto Rico) | 1,387.29 mi (2,232.62 km) |
| Orangeburg to San Juan (Texas) | 1,150.12 mi (1,850.94 km) |
| Orangeburg to San Juan Capistrano (California) | 2,108.22 mi (3,392.85 km) |
| Orangeburg to San Leandro (California) | 2,319.26 mi (3,732.48 km) |
| Orangeburg to San Lorenzo (California) | 2,318.03 mi (3,730.51 km) |
| Orangeburg to San Luis (Arizona) | 1,953.71 mi (3,144.19 km) |
