| Orangeburg to Salisbury (New York) | 642.25 mi (1,033.61 km) |
| Orangeburg to Salisbury (North Carolina) | 151.66 mi (244.07 km) |
| Orangeburg to Salmon Creek (Washington) | 2,348.31 mi (3,779.25 km) |
| Orangeburg to Salt Lake City (Utah) | 1,773.08 mi (2,853.49 km) |
| Orangeburg to Sammamish (Washington) | 2,336.83 mi (3,760.76 km) |
| Orangeburg to San Angelo (Texas) | 1,148.60 mi (1,848.50 km) |
| Orangeburg to San Anselmo (California) | 2,339.73 mi (3,765.43 km) |
| Orangeburg to San Antonio (Texas) | 1,075.51 mi (1,730.86 km) |
| Orangeburg to San Benito (Texas) | 1,125.09 mi (1,810.66 km) |
| Orangeburg to San Bernardino (California) | 2,080.32 mi (3,347.95 km) |
| Orangeburg to San Bruno (California) | 2,334.58 mi (3,757.15 km) |
| Orangeburg to San Buenaventura (California) | 2,188.02 mi (3,521.28 km) |
| Orangeburg to San Carlos (California) | 2,326.57 mi (3,744.25 km) |
| Orangeburg to San Carlos Park (Florida) | 488.11 mi (785.54 km) |
| Orangeburg to San Clemente (California) | 2,106.35 mi (3,389.84 km) |
