| Orangeburg to Reidsville (North Carolina) | 207.88 mi (334.55 km) |
| Orangeburg to Reisterstown (Maryland) | 469.34 mi (755.34 km) |
| Orangeburg to Rendon (Texas) | 949.19 mi (1,527.57 km) |
| Orangeburg to Reno (Nevada) | 2,186.98 mi (3,519.60 km) |
| Orangeburg to Renton (Washington) | 2,342.37 mi (3,769.67 km) |
| Orangeburg to Republic (Missouri) | 751.91 mi (1,210.08 km) |
| Orangeburg to Reston (Virginia) | 424.96 mi (683.91 km) |
| Orangeburg to Revere (Massachusetts) | 816.80 mi (1,314.51 km) |
| Orangeburg to Rexburg (Idaho) | 1,801.27 mi (2,898.86 km) |
| Orangeburg to Reynoldsburg (Ohio) | 459.29 mi (739.16 km) |
| Orangeburg to Rialto (California) | 2,085.94 mi (3,357.00 km) |
| Orangeburg to Richardson (Texas) | 915.40 mi (1,473.19 km) |
| Orangeburg to Richfield (Minnesota) | 1,027.47 mi (1,653.55 km) |
| Orangeburg to Richfield (Wisconsin) | 782.11 mi (1,258.68 km) |
| Orangeburg to Richland (Washington) | 2,193.70 mi (3,530.42 km) |
