| Orangeburg to Oxford (Alabama) | 288.08 mi (463.63 km) |
| Orangeburg to Oxford (Mississippi) | 500.31 mi (805.17 km) |
| Orangeburg to Oxford (Ohio) | 467.85 mi (752.93 km) |
| Orangeburg to Oxnard (California) | 2,186.11 mi (3,518.21 km) |
| Orangeburg to Oxon Hill (Maryland) | 425.44 mi (684.68 km) |
| Orangeburg to Ozark (Alabama) | 312.28 mi (502.56 km) |
| Orangeburg to Ozark (Missouri) | 737.73 mi (1,187.26 km) |
| Orangeburg to Pace (Florida) | 418.83 mi (674.04 km) |
| Orangeburg to Pacific Grove (California) | 2,314.70 mi (3,725.15 km) |
| Orangeburg to Pacifica (California) | 2,337.24 mi (3,761.42 km) |
| Orangeburg to Paducah (Kentucky) | 503.26 mi (809.92 km) |
| Orangeburg to Pahrump (Nevada) | 1,989.80 mi (3,202.28 km) |
| Orangeburg to Painesville (Ohio) | 569.11 mi (915.90 km) |
| Orangeburg to Palatine (Illinois) | 712.54 mi (1,146.73 km) |
| Orangeburg to Palatka (Florida) | 269.74 mi (434.10 km) |
