| Orangeburg to Odenton (Maryland) | 449.66 mi (723.66 km) |
| Orangeburg to Odessa (Texas) | 1,251.69 mi (2,014.39 km) |
| Orangeburg to Ogden (Utah) | 1,778.74 mi (2,862.60 km) |
| Orangeburg to Oildale (California) | 2,164.75 mi (3,483.83 km) |
| Orangeburg to Ojus (Florida) | 522.44 mi (840.79 km) |
| Orangeburg to Okemos (Michigan) | 664.94 mi (1,070.12 km) |
| Orangeburg to Oklahoma City (Oklahoma) | 956.70 mi (1,539.65 km) |
| Orangeburg to Okmulgee (Oklahoma) | 872.98 mi (1,404.93 km) |
| Orangeburg to Olathe (Kansas) | 861.34 mi (1,386.19 km) |
| Orangeburg to Old Jamestown (Missouri) | 641.62 mi (1,032.59 km) |
| Orangeburg to Oldsmar (Florida) | 390.93 mi (629.14 km) |
| Orangeburg to Olean (New York) | 608.08 mi (978.62 km) |
| Orangeburg to Olive Branch (Mississippi) | 522.73 mi (841.25 km) |
| Orangeburg to Olivehurst (California) | 2,279.51 mi (3,668.51 km) |
| Orangeburg to Olney (Maryland) | 444.01 mi (714.56 km) |
