| Orangeburg to Merriam (Kansas) | 858.47 mi (1,381.58 km) |
| Orangeburg to Merrick (New York) | 637.61 mi (1,026.14 km) |
| Orangeburg to Merrifield (Virginia) | 423.04 mi (680.82 km) |
| Orangeburg to Merrillville (Indiana) | 654.64 mi (1,053.54 km) |
| Orangeburg to Merritt Island (Florida) | 358.02 mi (576.17 km) |
| Orangeburg to Mesa (Arizona) | 1,771.93 mi (2,851.65 km) |
| Orangeburg to Mesquite (Nevada) | 1,883.71 mi (3,031.55 km) |
| Orangeburg to Mesquite (Texas) | 910.11 mi (1,464.69 km) |
| Orangeburg to Metairie (Louisiana) | 597.69 mi (961.88 km) |
| Orangeburg to Methuen Town (Massachusetts) | 826.16 mi (1,329.57 km) |
| Orangeburg to Metuchen (New Jersey) | 604.58 mi (972.97 km) |
| Orangeburg to Mexico (Missouri) | 726.26 mi (1,168.80 km) |
| Orangeburg to Miami (Florida) | 534.08 mi (859.52 km) |
| Orangeburg to Miami (Oklahoma) | 823.90 mi (1,325.94 km) |
| Orangeburg to Miami Beach (Florida) | 532.13 mi (856.38 km) |
