| Orangeburg to Medford (Massachusetts) | 813.31 mi (1,308.90 km) |
| Orangeburg to Medford (New York) | 666.31 mi (1,072.33 km) |
| Orangeburg to Medford (Oregon) | 2,343.31 mi (3,771.20 km) |
| Orangeburg to Medina (Ohio) | 530.93 mi (854.45 km) |
| Orangeburg to Medulla (Florida) | 388.21 mi (624.77 km) |
| Orangeburg to Mehlville (Missouri) | 630.89 mi (1,015.31 km) |
| Orangeburg to Melbourne (Florida) | 372.21 mi (599.01 km) |
| Orangeburg to Melissa (Texas) | 904.39 mi (1,455.48 km) |
| Orangeburg to Melrose (Massachusetts) | 816.67 mi (1,314.31 km) |
| Orangeburg to Melrose Park (Illinois) | 695.10 mi (1,118.66 km) |
| Orangeburg to Melville (New York) | 649.41 mi (1,045.12 km) |
| Orangeburg to Melvindale (Michigan) | 620.02 mi (997.83 km) |
| Orangeburg to Memphis (Florida) | 423.22 mi (681.10 km) |
| Orangeburg to Memphis (Tennessee) | 531.01 mi (854.58 km) |
| Orangeburg to Menasha (Wisconsin) | 844.11 mi (1,358.47 km) |
