| Orangeburg to McHenry (Illinois) | 732.40 mi (1,178.68 km) |
| Orangeburg to McKeesport (Pennsylvania) | 476.57 mi (766.97 km) |
| Orangeburg to McKinleyville (California) | 2,407.65 mi (3,874.74 km) |
| Orangeburg to McKinney (Texas) | 911.27 mi (1,466.55 km) |
| Orangeburg to McLean (Virginia) | 428.56 mi (689.70 km) |
| Orangeburg to McMinnville (Oregon) | 2,370.48 mi (3,814.92 km) |
| Orangeburg to McMinnville (Tennessee) | 317.90 mi (511.61 km) |
| Orangeburg to McNair (Virginia) | 423.39 mi (681.39 km) |
| Orangeburg to McPherson (Kansas) | 996.37 mi (1,603.51 km) |
| Orangeburg to Mead Valley (California) | 2,083.30 mi (3,352.75 km) |
| Orangeburg to Meadow Woods (Florida) | 355.10 mi (571.48 km) |
| Orangeburg to Meadowbrook (Virginia) | 332.31 mi (534.80 km) |
| Orangeburg to Meadville (Pennsylvania) | 564.81 mi (908.98 km) |
| Orangeburg to Mebane (North Carolina) | 200.64 mi (322.89 km) |
| Orangeburg to Mechanicsville (Virginia) | 347.08 mi (558.57 km) |
