| Orangeburg to Los Alamitos (California) | 2,127.51 mi (3,423.89 km) |
| Orangeburg to Los Alamos (New Mexico) | 1,449.42 mi (2,332.62 km) |
| Orangeburg to Los Altos (California) | 2,318.16 mi (3,730.71 km) |
| Orangeburg to Los Angeles (California) | 2,143.40 mi (3,449.47 km) |
| Orangeburg to Los Banos (California) | 2,251.61 mi (3,623.61 km) |
| Orangeburg to Los Gatos (California) | 2,311.50 mi (3,720.00 km) |
| Orangeburg to Los Lunas (New Mexico) | 1,480.36 mi (2,382.42 km) |
| Orangeburg to Los Osos (California) | 2,265.99 mi (3,646.76 km) |
| Orangeburg to Loudoun Valley Estates (Virginia) | 422.62 mi (680.15 km) |
| Orangeburg to Louisville (Colorado) | 1,411.61 mi (2,271.76 km) |
| Orangeburg to Louisville (Kentucky) | 419.40 mi (674.95 km) |
| Orangeburg to Lovejoy (Georgia) | 198.90 mi (320.11 km) |
| Orangeburg to Loveland (Colorado) | 1,413.48 mi (2,274.78 km) |
| Orangeburg to Loveland (Ohio) | 441.62 mi (710.71 km) |
| Orangeburg to Loves Park (Illinois) | 754.02 mi (1,213.48 km) |
