| Orangeburg to Lewiston (Idaho) | 2,087.50 mi (3,359.50 km) |
| Orangeburg to Lewiston (Maine) | 930.09 mi (1,496.84 km) |
| Orangeburg to Lewisville (North Carolina) | 182.15 mi (293.14 km) |
| Orangeburg to Lewisville (Texas) | 930.50 mi (1,497.49 km) |
| Orangeburg to Lexington (Kentucky) | 373.22 mi (600.64 km) |
| Orangeburg to Lexington (Nebraska) | 1,152.03 mi (1,854.02 km) |
| Orangeburg to Lexington (North Carolina) | 163.13 mi (262.53 km) |
| Orangeburg to Lexington (South Carolina) | 39.84 mi (64.11 km) |
| Orangeburg to Lexington Park (Maryland) | 411.62 mi (662.44 km) |
| Orangeburg to Liberal (Kansas) | 1,155.72 mi (1,859.96 km) |
| Orangeburg to Liberty (Missouri) | 850.86 mi (1,369.33 km) |
| Orangeburg to Liberty Lake (Washington) | 2,112.82 mi (3,400.26 km) |
| Orangeburg to Liberty Triangle (Florida) | 315.43 mi (507.64 km) |
| Orangeburg to Libertyville (Illinois) | 719.85 mi (1,158.48 km) |
| Orangeburg to Lighthouse Point (Florida) | 500.63 mi (805.68 km) |
