| Orangeburg to Laurinburg (North Carolina) | 118.26 mi (190.33 km) |
| Orangeburg to Lawndale (California) | 2,143.02 mi (3,448.86 km) |
| Orangeburg to Lawrence (Indiana) | 523.78 mi (842.94 km) |
| Orangeburg to Lawrence (Kansas) | 885.52 mi (1,425.10 km) |
| Orangeburg to Lawrence (Massachusetts) | 825.35 mi (1,328.26 km) |
| Orangeburg to Lawrenceburg (Kentucky) | 386.71 mi (622.34 km) |
| Orangeburg to Lawrenceburg (Tennessee) | 388.09 mi (624.58 km) |
| Orangeburg to Lawrenceville (Georgia) | 182.42 mi (293.58 km) |
| Orangeburg to Lawton (Oklahoma) | 1,006.53 mi (1,619.86 km) |
| Orangeburg to Layton (Utah) | 1,777.11 mi (2,859.99 km) |
| Orangeburg to Le Mars (Iowa) | 1,047.78 mi (1,686.24 km) |
| Orangeburg to League City (Texas) | 882.64 mi (1,420.47 km) |
| Orangeburg to Lealman (Florida) | 406.56 mi (654.30 km) |
| Orangeburg to Leander (Texas) | 1,014.44 mi (1,632.58 km) |
| Orangeburg to Leavenworth (Kansas) | 877.97 mi (1,412.96 km) |
