| Orangeburg to Laredo (Texas) | 1,179.39 mi (1,898.04 km) |
| Orangeburg to Largo (Florida) | 402.03 mi (647.01 km) |
| Orangeburg to Largo (Maryland) | 434.92 mi (699.93 km) |
| Orangeburg to Larkspur (California) | 2,337.90 mi (3,762.49 km) |
| Orangeburg to Las Cruces (New Mexico) | 1,501.90 mi (2,417.08 km) |
| Orangeburg to Las Vegas (Nevada) | 1,949.09 mi (3,136.76 km) |
| Orangeburg to Las Vegas (New Mexico) | 1,390.02 mi (2,237.01 km) |
| Orangeburg to Latham (New York) | 746.42 mi (1,201.25 km) |
| Orangeburg to Lathrop (California) | 2,272.55 mi (3,657.32 km) |
| Orangeburg to Lauderdale Lakes (Florida) | 507.65 mi (816.98 km) |
| Orangeburg to Lauderhill (Florida) | 508.07 mi (817.66 km) |
| Orangeburg to Laurel (Florida) | 448.27 mi (721.43 km) |
| Orangeburg to Laurel (Maryland) | 446.60 mi (718.73 km) |
| Orangeburg to Laurel (Mississippi) | 497.45 mi (800.56 km) |
| Orangeburg to Laurel (Virginia) | 343.00 mi (552.00 km) |
